The National Football League (NFL) is a professional American football league that consists of 32 teams, divided equally between the American Football Conference (AFC) and the National Football Conference (NFC). The NFL is one of the major professional sports leagues in the United States and Canada and the highest professional level of American football in the world. The league is headquartered in New York City.

Each NFL season begins with a three-week preseason in August, followed by the 18-week regular season which runs from early September to early January, with each team playing 17 games and having one bye week. Following the conclusion of the regular season, seven teams from each conference (four division winners and three wild card teams) advance to the playoffs, a single-elimination tournament that culminates in the Super Bowl, which is contested in February and is played between the AFC and NFC conference champions.

The NFL was formed in 1920 as the American Professional Football Association (APFA) before renaming itself the National Football League for the 1922 season. After initially determining champions through end-of-season standings, a playoff system was implemented in 1933 that culminated with the NFL Championship Game until 1966. Following an agreement to merge the NFL with the rival American Football League (AFL), the Super Bowl was first held in 1967 to determine a champion between the best teams from the two leagues and has remained as the final game of each NFL season since the merger was completed in 1970.

The NFL is the wealthiest professional sports league in the world by revenue and the sports league with the most valuable teams. The NFL also has the highest average attendance (67,591) of any professional sports league in the world and is the most popular sports league in the United States. The Super Bowl is also among the biggest club sporting events in the world, with the individual games accounting for many of the most watched television programs in American history and all occupying the Nielsen's Top 5 tally of the all-time most watched U.S. television broadcasts by 2015.

The Green Bay Packers hold the most combined NFL championships with thirteen, winning nine titles before the Super Bowl era and four Super Bowls afterwards. Since the creation of the Super Bowl, the New England Patriots and Pittsburgh Steelers are tied for the most Super Bowl victories at six each. The Kansas City Chiefs are the reigning league champions, as they defeated the Philadelphia Eagles 38–35 in Super Bowl LVII on February 12, 2023, to mark the end of the 2022 season.